Selectively merge overlapping cores based on score difference.

This function takes a GRanges object of genomic cores, sorts them by descending score, and merges overlapping cores if their score difference is within a specified threshold.

Usage

selective_merge_cores(core_gr, score_diff)

Arguments

core_gr

A GRanges object containing genomic core ranges.

score_diff

A numeric value specifying the maximum allowed score difference for merging overlapping cores.

Value

A GRanges object with merged core regions and added metadata, including the thick position and maximum score.