Calculate the cumulative fraction of CTSSs around loci, considering unique tags and the fraction of loci with CTSSs.

Calculate the cumulative fraction of CTSSs around loci, considering unique tags and the fraction of loci with CTSSs.

Usage

cumulativeFractionsAroundLoci(
  loci,
  ctss,
  max_dist = 1000,
  inputAssay = "counts"
)

Arguments

loci

A GRanges object of loci to focus on.

ctss

A RangedSummarizedExperiment object containing the CTSSs.

max_dist

The number of base pairs to consider around each locus.

inputAssay

The assay in the ctss object to use for counting tags (default is "counts").

Value

A list of three data frames: cumulative fraction of tags, cumulative fraction of unique tags, and cumulative fraction of loci with CTSSs, for each sample.