Decompose tag cluster into subclusters according to CTSS expression correlation across samples. — corr_decompose • PRIME

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Decompose tag cluster into subclusters according to CTSS expression correlation across samples.

Usage

corr_decompose(
  rse,
  gr,
  assay = "TPM",
  thres = 0.25,
  merge = TRUE,
  scale = TRUE
)

Arguments

rse: A RangedSummarizedExperiment object containing the CTSSs.
gr: A GRanges object of tag clusters.
assay: The assay to use for the correlation calculation.
thres: The threshold for the Bayesian change point analysis.
merge: If TRUE, subclusters will be merged if positively correlated.
scale: If TRUE, the assay values will be scaled before correlation calculation.

Value

An IRanges object of decomposed tag clusters.